A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures
Limin Yang, Xuehan Yin, Panpan Gai, Feng Li
Abstract
We developed a label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, which avoided expensive labeling and sophisticated immobilization procedures, providing opportunities for precisely detecting cancer cells in clinical applications.
Topics & Concepts
HomogeneousNanostructureNanotechnologyTetrahedronElectrochemistryDNACombinatorial chemistryCancer cellMaterials scienceChemistryCancerBiologyBiochemistryElectrodeCrystallographyMathematicsPhysical chemistryGeneticsCombinatoricsAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionNanopore and Nanochannel Transport Studies