AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence
SangJoon Lee, Rajendra Karki, Yaqiu Wang, Lam Nhat Nguyen, Ravi Kalathur, Thirumala‐Devi Kanneganti
Topics & Concepts
AIM2Pyrin domainInflammasomeInnate immune systemBiologyCaspase 1Programmed cell deathNALP3RIPK1Cell biologyImmunologyImmune systemNecroptosisInflammationApoptosisGeneticsInflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation