Aerobic exercise regulates GPR81 signal pathway and mediates complement- microglia axis homeostasis on synaptic protection in the early stage of Alzheimer's disease
Jialun Yang, Shunling Yuan, Ye Jian, Yong Lei, Zelin Hu, Qiming Yang, Xinjun Yan, Lan Zheng, Jiang-Hua Li, Wenfeng Liu
Topics & Concepts
MicrogliaAerobic exerciseBiologyDendritic spineInternal medicineSynaptic plasticityEndocrinologyNeuroscienceCell biologyReceptorMedicineInflammationHippocampal formationNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms