Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation
Shaoyang Zhang, Xuemin Guo, Xiufeng Liu, Zhixiong Zhong, Shulan Yang, Haihe Wang
Topics & Concepts
Cancer researchDownregulation and upregulationPTENBiologyProtein kinase BPI3K/AKT/mTOR pathwayWnt signaling pathwayMetastasisBreast cancerUbiquitin ligaseCarcinogenesisSignal transductionCancerUbiquitinCell biologyGeneticsBiochemistryGeneUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysMicrotubule and mitosis dynamics