Redox-responsive nanogels for drug-delivery: thiol–maleimide and thiol–disulfide exchange chemistry as orthogonal tools for fabrication and degradation
Ismail Altinbasak, Salli Kocak, Rana Sanyal, Amitav Sanyal
Abstract
Redox-responsive nanogels are prepared by exploiting the orthogonal reactivity of thiol–maleimide and thiol–disulfide exchange reactions.
Topics & Concepts
MaleimideThiolChemistryDisulfide bondRedoxDegradation (telecommunications)Drug deliveryCombinatorial chemistryPolymer chemistryOrganic chemistryBiochemistryComputer scienceTelecommunicationsNanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsDendrimers and Hyperbranched Polymers