A near-infrared GPX4 fluorescent probe for non-small cell lung cancer imaging
Qiao Hu, Wanjie Zhu, Jianjun Du, Saran Long, Wen Sun, Jiangli Fan, Xiaojun Peng
Abstract
A near-infrared fluorescent probe ENBO-ML210 was developed. In vitro and in vivo imaging results showed that it could target and visualize GPX4 in H1299 cells, exhibiting the potential for diagnosis of non-small lung cancer.
Topics & Concepts
FluorescenceGPX4In vivoLung cancerIn vitroGlutathioneCancer cellChemistryCancer researchCellCancerPathologyBiophysicsGlutathione peroxidaseBiochemistryBiologyMedicineEnzymeOpticsInternal medicinePhysicsBiotechnologyNanoplatforms for cancer theranosticsInflammatory mediators and NSAID effectsSulfur Compounds in Biology