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An antibacterial chitosan-based hydrogel as a potential degradable bio-scaffold for alveolar ridge preservation

Xiaoyu Zhou, Congrui Liu, Yijun Han, Can Li, Sida Liu, Xiaoyan Li, Guoqing Zhao, Yanyan Jiang

2022RSC Advances27 citationsDOIOpen Access PDF

Abstract

was above 90%, which could effectively inhibit the spread of the bacteria and inflammation in the alveolar ridge. Additionally, the hybrid hydrogels demonstrated good biocompatibility with the NIH 3T3 fibroblast cells. Overall, the CS/PEG/PHMB hydrogel is a promising biological scaffold for maintaining the alveolar ridge and subsequently improving the success rate of the dental implant.

Topics & Concepts

Self-healing hydrogelsChitosanPEG ratioBiocompatibilityEthylene glycolSwellingChemistryScaffoldAntibacterial activityCompressive strengthChemical engineeringFibroblastBiomedical engineeringMaterials scienceNuclear chemistryIn vitroBacteriaPolymer chemistryComposite materialOrganic chemistryBiochemistryBiologyEngineeringEconomicsGeneticsMedicineFinanceBone Tissue Engineering MaterialsDental Implant Techniques and OutcomesPeriodontal Regeneration and Treatments
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