Melatonin loaded PLGA nanoparticles effectively ameliorate the <i>in vitro</i> maturation of deteriorated oocytes and the cryoprotective abilities during vitrification process
Sujin Lee, Hye Jin Kim, Hui Bang Cho, Hye-Ryoung Kim, Sujeong Lee, Ji-In Park, Keun‐Hong Park
Abstract
A strategy for effectively improving oocyte quality and cryotolerance during vitrification via nanoparticle-mediated melatonin delivery is reported.
Topics & Concepts
VitrificationMelatoninIn vitroChemistryPLGABiophysicsNanoparticleCell biologyAndrologyBiochemistryNanotechnologyBiologyMaterials scienceEndocrinologyMedicineSeed Germination and PhysiologyReproductive Biology and FertilitySperm and Testicular Function