Evaluation of the binding behavior of olmutinib (HM61713) with model transport protein: Insights from spectroscopic and molecular docking studies
Song‐Bo Kou, Zhen‐Yi Lin, Baoli Wang, Jie‐Hua Shi, Ying-Xin Liu
Topics & Concepts
ChemistryBovine serum albuminDocking (animal)van der Waals forceHydrogen bondHydrophobic effectBinding siteMolecular modelQuenching (fluorescence)Binding constantFluorescenceStereochemistryBiophysicsMoleculeBiochemistryOrganic chemistryMedicinePhysicsBiologyNursingQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisMetal complexes synthesis and propertiesDrug Transport and Resistance Mechanisms