lncRNA MIR503HG inhibits cell proliferation and promotes apoptosis in TNBC cells via the miR-224-5p/HOXA9 axis
Shou-Man Wang, Jian Pang, Kejing Zhang, Zhiyang Zhou, Feiyu Chen
Abstract
study proved that MIR503HG inhibited TNBC tumor growth via the miR-224-5p/HOXA9 axis. MIR503HG inhibited cell proliferation and promoted the apoptosis of TNBC cells via the miR-224-5p/HOXA9 axis, which may function as a novel target for the treatment of TNBC.
Topics & Concepts
Gene knockdownCancer researchTriple-negative breast cancerCell growthApoptosisHomeobox A1Cell migrationFlow cytometryBreast cancerCellBiologyChemistryHomeoboxCancerMolecular biologyGene expressionGeneBiochemistryGeneticsCancer-related molecular mechanisms researchCircular RNAs in diseasesMicroRNA in disease regulation