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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

Bruno Coutard, Coralie Valle, Xavier de Lamballerie, Bruno Canard, Nabil G. Seidah, Étienne Decroly

2020Antiviral Research1,838 citationsDOI

Topics & Concepts

FurinVirologyCoronavirusBiologyGenomeCleavage (geology)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GlycoproteinCoronavirus disease 2019 (COVID-19)BetacoronavirusPandemicGeneticsCladeComputational biologyGenePhylogenetic treeInfectious disease (medical specialty)MedicineBiochemistryDiseasePathologyFracture (geology)PaleontologyEnzymeSARS-CoV-2 and COVID-19 Researchinterferon and immune responsesAnimal Virus Infections Studies
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade | Litcius