Litcius/Paper detail

Bone metabolism regulation: Implications for the treatment of bone diseases

Danqi Yao, Lianfang Huang, Jianhao Ke, Ming Zhang, Qin Xiao, Xiao Zhu

2020Biomedicine & Pharmacotherapy39 citationsDOIOpen Access PDF

Abstract

Bone cells in the human body are continuously engaged in cellular metabolism, including the interaction between bone cells, the interaction between the erythropoietic cells of the bone marrow and stromal cells, for the remodeling and reconstruction of bone. Osteoclasts and osteoblasts play an important role in bone metabolism. Diseases occur when bone metabolism is abnormal, but little is known about the signaling pathways that affect bone metabolism. The study of these signaling pathways will help us to use the relevant techniques to intervene, so as to improve the condition. The study of these signaling pathways will help us to use the relevant techniques to intervene, so as to improve the condition. I believe they will shine in the diagnosis and treatment of future clinical bone diseases.

Topics & Concepts

Bone remodelingStromal cellBone marrowSignal transductionBone cellCell metabolismMetabolismBone formationOsteoporosisMedicineCell biologyBioinformaticsCancer researchBiologyEndocrinologyInternal medicineBone Metabolism and DiseasesBone health and treatmentsBone and Joint Diseases