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Chemokine receptor 4 targeted protein MRI contrast agent for early detection of liver metastases

Shanshan Tan, Hua Yang, Shenghui Xue, Jingjuan Qiao, Mani Salarian, Khan Hekmatyar, Y. H. Meng, Rao Mukkavilli, Fan Pu, Oluwatosin Y. Odubade, Wayne Harris, Yan Hai, Melinda Yushak, Vanessa Morales-Tirado, Pardeep Mittal, Phillip Zhe Sun, David H. Lawson, Hans E. Grossniklaus, Jenny J. Yang

2020Science Advances29 citationsDOIOpen Access PDF

Abstract

. Further development of the CXCR4-targeted imaging agent should have strong translation potential for early detection, surveillance, and treatment stratification of liver metastases patients.

Topics & Concepts

Magnetic resonance imagingContrast (vision)ChemokineMRI contrast agentChemokine receptorMedicineReceptorPathologyRadiologyComputer scienceInternal medicineArtificial intelligenceNanoplatforms for cancer theranosticsChemokine receptors and signalingAdvanced Biosensing Techniques and Applications
Chemokine receptor 4 targeted protein MRI contrast agent for early detection of liver metastases | Litcius