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Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

Liming Yan, Yunxiang Yang, Mingyu Li, Ying Zhang, Litao Zheng, Ji Ge, Yucen Huang, Zhenyu Liu, Tao Wang, Shan Gao, Ran Zhang, Yuanyun Huang, Luke W. Guddat, Yan Gao, Zihe Rao, Zhiyong Lou

2021Cell153 citationsDOIOpen Access PDF

Topics & Concepts

ProofreadingBiologyExoribonucleaseGeneticsPolymeraseCoupling (piping)Cell biologyDNAGeneRNAMechanical engineeringRNase PEngineeringEnzyme Structure and FunctionDNA Repair MechanismsCancer Research and Treatments
Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading | Litcius