Manufacturing, characterization, and degradation of a poly(lactic acid) warp-knitted spacer fabric scaffold as a candidate for tissue engineering applications
Flavia Caronna, Nikola Glimpel, Georg-Philipp Paar, Thomas Gries, Andreas Blaeser, Khoa Do, Eimear B. Dolan, William Ronan
Abstract
culture by 4',6-diamidino-2-phenylindole (DAPI) fluorescent staining and DNA quantification. The present work shows the potential of spacer fabric scaffolds as a versatile and scalable scaffold fabrication technique, having the ability to create a microenvironment with appropriate physical, mechanical, and degradation properties for 3D tissue engineering. The high control and tunability of spacer fabric properties makes it a promising candidate for the regeneration of different tissues in patient-specific applications.
Topics & Concepts
ScaffoldDegradation (telecommunications)Characterization (materials science)Lactic acidTissue engineeringChemistryMaterials scienceComputer scienceBiomedical engineeringNanotechnologyEngineeringBiologyBacteriaGeneticsTelecommunicationsAdditive Manufacturing and 3D Printing TechnologiesElectrospun Nanofibers in Biomedical Applicationsbiodegradable polymer synthesis and properties