Uncommon Four‐Membered Building Blocks – Cyclobutenes, Azetines and Thietes
Dorian Didier, Felix Reiners
Abstract
Strained ring systems have gained considerable importance over the last few years for their implication in natural product syntheses or in drug discovery programs. We present herein a recollection of our work on the construction and functionalization of unsaturated four-membered carbo- and heterocycles in the context of the literature, as well as their applications in further reactions.
Topics & Concepts
Context (archaeology)Natural productRing (chemistry)Computer scienceNatural (archaeology)Combinatorial chemistryChemistryStereochemistryOrganic chemistryBiologyPaleontologyCyclopropane Reaction MechanismsSynthesis and Catalytic ReactionsSynthesis and Biological Evaluation