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Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway

Yu Ma, Siwen Li, Sixuan Tang, Shuzi Ye, Ningjuan Liang, Yuehui Liang, Fang Xiao

2022Environmental Science and Pollution Research14 citationsDOI

Topics & Concepts

Oxidative stressProtein kinase BKEAP1ClusterinReactive oxygen speciesThioredoxin reductasePI3K/AKT/mTOR pathwayChemistryCytoprotectionHeme oxygenaseSignal transductionApoptosisCell biologyBiologyHemeBiochemistryThioredoxinTranscription factorGeneEnzymeClusterin in disease pathologyBiomarkers in Disease MechanismsMedicinal Plants and Bioactive Compounds
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway | Litcius