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NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway

Jung-Eun Park, Jin‐Sun Park, Yea-Hyun Leem, Do‐Yeon Kim, Hee-Sun Kim

2021Free Radical Biology and Medicine55 citationsDOI

Topics & Concepts

NeuroinflammationChemistryAMPKp38 mitogen-activated protein kinasesSignal transductionReactive oxygen speciesLipopolysaccharideProtein kinase BDownregulation and upregulationCell biologyOxidative stressProinflammatory cytokinePharmacologyInflammationMAPK/ERK pathwayProtein kinase ABiochemistryBiologyImmunologyKinaseGeneNeuroinflammation and Neurodegeneration MechanismsGenomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents
NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway | Litcius