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TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence

Lei Fang, Dongmei Li, JuanJuan Yin, Hong Pan, Huihui Ye, Joel Bowman, Brian J. Capaldo, Kathleen Kelly

2022Cancer Gene Therapy22 citationsDOIOpen Access PDF

Topics & Concepts

TMPRSS2Cancer researchPTENCarcinogenesisBiologyErgOncogeneSenescenceKRASProstate cancerProstatePI3K/AKT/mTOR pathwayCancerGeneMutationSignal transductionCell biologyCell cycleGeneticsMedicineInternal medicineDiseaseInfectious disease (medical specialty)RetinaNeuroscienceCoronavirus disease 2019 (COVID-19)Prostate Cancer Treatment and ResearchHippo pathway signaling and YAP/TAZCancer-related Molecular Pathways
TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence | Litcius