Lifetime risk of rheumatoid arthritis-associated interstitial lung disease in MUC5B mutation carriers
Antti Palomäki, Aarno Palotie, Jukka Koskela, Kari K. Eklund, Matti Pirinen, Samuli Ripatti, Tarja Laitinen, Nina Mars
Abstract
OBJECTIVES: promoter variant. METHODS: promoter variant. RESULTS: non-carriers. The difference between risks started to emerge at age 65, with a higher risk among men. CONCLUSION: mutation carrier status, demonstrating the potential of genomics for risk stratification of RA-ILD.
Topics & Concepts
MedicineRheumatoid arthritisInterstitial lung diseaseMutationLungImmunologyInternal medicineGeneticsGeneBiologyInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisAntifungal resistance and susceptibilityPneumocystis jirovecii pneumonia detection and treatment