Selective delivery of curcumin to breast cancer cells by self-targeting apoferritin nanocages with pH-responsive and low toxicity
Peng Ji, Xianglong Wang, Jiabing Yin, Yi Mou, Haiqin Huang, Zhenkun Ren
Abstract
therapeutic effect and lower systemic toxicity. The safety evaluation results indicated that Cur@HFn has no hematotoxicity, hepatotoxicity, and nephrotoxicity. The findings of the present study showed that the Cur@HFn has been successfully prepared and has potential application value in the treatment of breast cancer.
Topics & Concepts
CurcuminPharmacologyCytotoxicityToxicityApoptosisDrug deliveryCancerBreast cancerMedicineBioavailabilityMaterials scienceIn vitroChemistryNanotechnologyBiochemistryInternal medicineRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers