Biological function investigated by time-resolved structure determination
Marius Schmidt
Abstract
Inspired by recent progress in time-resolved x-ray crystallography and the adoption of time-resolution by cryo-electronmicroscopy, this article enumerates several approaches developed to become bigger/smaller, faster, and better to gain new insight into the molecular mechanisms of life. This is illustrated by examples where chemical and physical stimuli spawn biological responses on various length and time-scales, from fractions of Ångströms to micro-meters and from femtoseconds to hours.
Topics & Concepts
FemtosecondAngstromSpawn (biology)Computer scienceBiological systemResolution (logic)NanotechnologyAlgorithmMaterials scienceChemistryPhysicsOpticsArtificial intelligenceCrystallographyBiologyLaserFisheryAdvanced Electron Microscopy Techniques and Applicationsbioluminescence and chemiluminescence researchEnzyme Structure and Function