Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
Megan Rowton, Carlos Perez-Cervantes, Suzy S. J. Hur, Jessica Jacobs-Li, Emery Lu, Nikita Deng, Alexander Guzzetta, Andrew D. Hoffmann, Matthew Stocker, Jeffrey D. Steimle, Sonja Lazarevic, Sophie Oubaha, Xinan Yang, Chul Kim, Shu‐Han Yu, Heather Eckart, Mervenaz Koska, Erika Hanson, Sunny Sun-Kin Chan, Daniel J. Garry, Michael Kyba, Anindita Basu, Kohta Ikegami, Sebastian Pott, Ivan P. Moskowitz
Topics & Concepts
BiologyProgenitorProgenitor cellHedgehogHeterochronyHedgehog signaling pathwayCellular differentiationCell biologyGLI1Transcription factorSonic hedgehogPatchedSignal transductionGeneticsStem cellGeneOntogenyHedgehog Signaling Pathway StudiesGenetics and Neurodevelopmental DisordersCongenital heart defects research