Stereoselective synthesis of fused-, spiro- and bridged heterocycles <i>via</i> cyclization of isoquinolinium salts: a recent update

Abstract

generated isoquinolinium salts. Most of the reactions described here provide quick access to the desired products with high stereoselectivity starting from readily available starting materials under mild conditions. The synthetic potential of most of the transformations was confirmed by the gram-scale production of the target molecules. Some of the reactions have been useful for the synthesis of natural products and other bioactive compounds.

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