Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state
C. Bassand, L. Benabed, J. Vérin, Florence Danède, L.A. Lefol, Jean‐François Willart, F. Siepmann, Juergen Siepmann
Topics & Concepts
PLGAPolymerMaterials scienceExtrusionGravimetric analysisPenetration (warfare)ImplantPolymer degradationSwellingThermogravimetric analysisDrug deliveryScanning electron microscopeChemical engineeringBiomedical engineeringChemistryComposite materialNanotechnologyNanoparticleOrganic chemistrySurgeryMedicineOperations researchEngineeringAdvanced Drug Delivery SystemsBone Tissue Engineering Materialsbiodegradable polymer synthesis and properties