Eleutheroside A inhibits PI3K/AKT1/mTOR-mediated glycolysis in MDSCs to alleviate their immunosuppressive function in gastric cancer
Xiaotao Jiang, Aimin Wu, Jiaxing Yan, Jingming Chen, Yi Wen, Hui Wu, Ning Yan, Zehong Yang, Fengbin Liu, Peiwu Li
Topics & Concepts
PI3K/AKT/mTOR pathwayCancerAKT1Function (biology)Discovery and development of mTOR inhibitorsGlycolysisCancer researchMedicineBiologySignal transductionCell biologyMetabolismInternal medicineNatural product bioactivities and synthesisPhytochemical Studies and BioactivitiesTraditional Chinese Medicine Analysis