Avian and Human Influenza A Virus Receptors in Bovine Mammary Gland
Charlotte Kristensen, Henrik Elvang Jensen, Ramona Trebbien, Richard J. Webby, Lars Erik Larsen
Abstract
An outbreak of influenza A (H5N1) virus was detected in dairy cows in the United States. We detected influenza A virus sialic acid -α2,3/α2,6-galactose host receptors in bovine mammary glands by lectin histochemistry. Our results provide a rationale for the high levels of H5N1 virus in milk from infected cows.
Topics & Concepts
Influenza A virus subtype H5N1VirologyVirusSialic acidMammary glandBiologyReceptorHost (biology)NeuraminidaseMicrobiologyInfluenza A virusOutbreakH5N1 genetic structureAvian influenza virusInternal medicineMedicineCoronavirus disease 2019 (COVID-19)BiochemistryEcologyGeneticsBreast cancerInfectious disease (medical specialty)DiseaseCancerInfluenza Virus Research StudiesGlycosylation and Glycoproteins ResearchImmune Response and Inflammation