Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
Alicja Krakowiak, Jakub Kuleta, Iwona Plech, Maciej Zarębiński, Małgorzata Wojciechowska, Dominik Wretowski, Agnieszka Cudnoch-Jędrzejewska
Abstract
With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms.
Topics & Concepts
TicagrelorMedicineBradycardiaDifferential diagnosisDrugCardiologyIntensive care medicineInternal medicineAcute coronary syndromePharmacologyPathologyMyocardial infarctionHeart rateBlood pressureAntiplatelet Therapy and Cardiovascular DiseasesAtrial Fibrillation Management and OutcomesVenous Thromboembolism Diagnosis and Management