Litcius/Paper detail

Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities

Youzhi Wang, Guoqing Yang, Hui-Zhen Shen, Ying Liang, Haijuan Dong, Ximing Guo, Qingjing Hao, Jinxin Wang, Jinxin Wang

2024European Journal of Medicinal Chemistry13 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryEdaravoneDPPHAntioxidantFree radical scavengerPharmacologyCelecoxibLipid peroxidationHydroxyl radicalIC50BiochemistryIn vitroMedicineInflammatory mediators and NSAID effectsSynthesis and biological activityEicosanoids and Hypertension Pharmacology
Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities | Litcius