Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice
Daniel A. Mordes, Brett M. Morrison, Xanthe Heifetz Ament, C. Ron Cantrell, Joanie Mok, Pierce Eggan, Carolyn Xue, Jinyuan Wang, Kevin Eggan, Jeffrey D. Rothstein
Topics & Concepts
C9orf72Amyotrophic lateral sclerosisFrontotemporal dementiaNeurodegenerationTransgenePhenotypeTrinucleotide repeat expansionNeuroscienceBiologyGenetically modified mouseMotor neuronTARDBPGeneticsDementiaDiseaseMedicineGenePathologyAlleleSpinal cordAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders ResearchPrion Diseases and Protein Misfolding