Dexmedetomidine exerts cerebral protective effects against cerebral ischemic injury by promoting the polarization of M2 microglia via the Nrf2/HO-1/NLRP3 pathway
Ning Wang, Huan Nie, Yueyue Zhang, Huiying Han, Shan Wang, Wenjuan Liu, Kuo Tian
Topics & Concepts
MicrogliaNeuroprotectionPharmacologyOxidative stressMedicineInflammationIschemiaAnesthesiaIn vivoDexmedetomidineEndocrinologyInternal medicineBiologySedationBiotechnologyNeuroinflammation and Neurodegeneration MechanismsGenomics, phytochemicals, and oxidative stressInflammasome and immune disorders