A distinct GM-CSF <sup>+</sup> T helper cell subset requires T-bet to adopt a T <sub>H</sub> 1 phenotype and promote neuroinflammation
Javad Rasouli, Giacomo Casella, Satoshi Yoshimura, Weifeng Zhang, Dan Xiao, James Garifallou, Michael V. Gonzalez, Alice Wiedeman, Anna Kus, Elisabeth R. Mari, Paolo Fortina, Håkon Håkonarson, S. Alice Long, Guang‐Xian Zhang, Bogoljub Ćirić, Abdolmohamad Rostami
Abstract
A GM-CSF + T helper cell subset develops from naïve precursors and switch to a T H 1 phenotype during neuroinflammation.
Topics & Concepts
PhenotypeT helper cellNeuroinflammationT cellImmunologyBiologyCell biologyMolecular biologyGeneGeneticsImmune systemInflammationT-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesImmune Cell Function and Interaction