Stability of antibody drug conjugate formulations evaluated using solid-state hydrogen-deuterium exchange mass spectrometry
Eunbi Cho, Brendan M. Mayhugh, Jayasree Srinivasan, Gregory A. Sacha, Steven L. Nail, Elizabeth M. Topp
Topics & Concepts
ChemistryMass spectrometryConjugateAntibody-drug conjugateChromatographyHydrogen–deuterium exchangeDeuteriumDrugAntibodyMonoclonal antibodyPharmacologyMedicineBiologyQuantum mechanicsMathematicsMathematical analysisImmunologyPhysicsMonoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityMass Spectrometry Techniques and Applications