Ambulatory thyroidectomy is safe and beneficial in papillary thyroid carcinoma: Randomized controlled trial
Zeyu Zhang, Fada Xia, Wenlong Wang, Bo Jiang, Lei Yao, Yun Huang, Xinying Li
Abstract
BACKGROUND: Currently, no randomized controlled trial has been performed to investigate the safety profiles, economic benefit and mental health of ambulatory thyroidectomy in patients with papillary thyroid carcinoma (PTC). METHODS: Patients diagnosed with PTC were enrolled in this study and were randomly assigned to ambulatory group and control group. The safety profiles, economic benefit and mental health were investigated. RESULTS: Four hundred and eleven patients completed the study. There was no significant difference in demographic or tumor index. The incidence of complications was not significantly different (P = .631). The economic cost was significantly lower (P < .001) and hospitalization was significantly shorter (P < .001) in ambulatory group. No significant difference was shown in depression (P = .758) and stress disorder (P = .390). However, the ambulatory group showed a higher point of anxiety (P < .001). CONCLUSION: The ambulatory thyroidectomy is safe in patients with PTC, with significant benefits of economic cost and hospitalization.