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Hepatoprotective potential of gabapentin in cecal ligation and puncture-induced sepsis; targeting oxidative stress, apoptosis, and NF-kB/MAPK signaling pathways

Mahmoud Abdelnaser, Rania Alaaeldin, Mina Ezzat Attya, Moustafa Fathy

2023Life Sciences36 citationsDOI

Topics & Concepts

Proinflammatory cytokineSepsisMAPK/ERK pathwayOxidative stressApoptosisPharmacologyTumor necrosis factor alphaMedicineImmunologyInflammationSignal transductionBiologyInternal medicineBiochemistryDrug-Induced Hepatotoxicity and ProtectionImmune Response and InflammationCell death mechanisms and regulation
Hepatoprotective potential of gabapentin in cecal ligation and puncture-induced sepsis; targeting oxidative stress, apoptosis, and NF-kB/MAPK signaling pathways | Litcius