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Acute CNS demyelination in a subject with cerebellar ataxia following the first dose of COVID-19 vaccine; a case report

Omid Mirmosayyeb, Sara Bagherieh, Vahid Shaygannejad

2021Human Vaccines & Immunotherapeutics13 citationsDOIOpen Access PDF

Abstract

Vaccination-induced demyelination is a rare, unusual side effect of certain vaccines which can cause significant damage to patient's sensory-motor abilities within days. Although COVID-19 vaccines go through rigorous clinical trials before they are injected to the general population, certain unexpected side effects remain inevitable. We herein describe a case of a 42-year-old woman who experienced acute demyelination 10 days after the Oxford-AstraZeneca vaccination. To the best of our knowledge, this is the first case of such nature and severity described regarding COVID-19 vaccines' side effects.

Topics & Concepts

MedicineVaccinationCoronavirus disease 2019 (COVID-19)AtaxiaPediatricsPopulationMultiple sclerosis2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyVirologyPathologyOutbreakDiseasePsychiatryInfectious disease (medical specialty)Environmental healthPeripheral Neuropathies and DisordersMultiple Sclerosis Research StudiesLong-Term Effects of COVID-19
Acute CNS demyelination in a subject with cerebellar ataxia following the first dose of COVID-19 vaccine; a case report | Litcius