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Severity of central sleep apnea does not affect sleeping oxygen saturation during ascent to high altitude

Jordan D. Bird, Anne Kalker, Alexander Rimke, Jason Chan, Garrick Chan, Gurkarn Saran, Nicholas Jendzjowsky, Richard J. A. Wilson, Thomas D. Brutsaert, Mingma Sherpa, Trevor A. Day

2021Journal of Applied Physiology16 citationsDOI

Abstract

Central sleep apnea (CSA) is universal during ascent to high altitude, with intermittent and transient fluctuations in oxygen saturation, but the consequences on mean sleeping blood oxygenation are unclear. We assessed indices of CSA and mean sleeping peripheral oxygen saturation ([Formula: see text]) during ascent to high altitude using two ascent profiles: rapid ascent and residence at 3,800 m and incremental ascent to 5,160 m. The severity of CSA was not correlated with mean sleeping [Formula: see text] with ascent.

Topics & Concepts

HyperventilationApneaCentral sleep apneaPeriodic breathingEffects of high altitude on humansAnesthesiaMedicineOxygen saturationHypocapniaSleep apneaHypopneaPolysomnographyCardiologyOxygenChemistryHypercapniaAcidosisAnatomyOrganic chemistryHigh Altitude and HypoxiaNeuroscience of respiration and sleepObstructive Sleep Apnea Research