Structural basis for the Mg <sup>2+</sup> recognition and regulation of the CorC Mg <sup>2+</sup> transporter
Yichen Huang, Fei Jin, Yosuke Funato, Zhijian Xu, Weiliang Zhu, Jing Wang, Minxuan Sun, Yimeng Zhao, Ye Yu, Hiroaki Miki, Motoyuki Hattori
Abstract
Crystal structures of the CorC Mg 2+ transporter revealed the unique Mg 2+ binding site associated with genetic diseases.
Topics & Concepts
TransporterChemistryBiochemistryGeneMagnesium in Health and DiseaseMechanisms of cancer metastasisParathyroid Disorders and Treatments