Obstructive sleep apnea in sarcoidosis and impact of cpap treatment on fatigue.
Pier‐Valerio Mari, Giuliana Pasciuto, Matteo Siciliano, Jacopo Simonetti, Federico Ballacci, Francesco Macagno, Bruno Iovene, F Martone, Giuseppe Maria Corbo, Luca Richeldi
Abstract
RATIONALE: An increased incidence of Obstructive Sleep Apnea (OSA) in sarcoidosis has been described in small sample size studies. Fatigue is common in sarcoidosis and OSA could be a relevant, treatable comorbidity. To date, the effect of Continuous Positive Airway Pressure (CPAP) on fatigue has never been assessed. OBJECTIVES: To investigate the prevalence of OSA in sarcoidosis, fatigue status and daytime sleepiness in patients of our center. To explore the effect of CPAP in fatigue and daytime sleepiness after 3 months using validated questionnaires. METHOD: Single group, one center, open-label prospective cohort study. MEASUREMENTS AND MAIN RESULT: = 2.8; p = 0.005) improved after three months of CPAP. CONCLUSIONS: .