TXNIP Regulates NLRP3 Inflammasome-Induced Pyroptosis Related to Aging via cAMP/PKA and PI3K/Akt Signaling Pathways
Xiaoshuang Xi, Rong Zhang, Yijia Chi, Ziman Zhu, Ruifeng Sun, Weijun Gong
Topics & Concepts
PyroptosisTXNIPInflammasomePI3K/AKT/mTOR pathwayProtein kinase BActivator (genetics)Cell biologyLY294002Proinflammatory cytokineCancer researchChemistrySignal transductionMedicineBiologyImmunologyInflammationBiochemistryReceptorOxidative stressThioredoxinInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxide