Discovery of a novel series of substituted quinolines acting as anticancer agents and selective EGFR blocker: Molecular docking study
C.B. Pradeep Kumar, M.S. Raghu, B.S. Prathibha, M.K. Prashanth, G. Kanthimathi, K. Yogesh Kumar, L. Parashuram, Fahad A. Alharthi
Topics & Concepts
ChemistryDocking (animal)Lipinski's rule of fiveCombinatorial chemistryEpidermal growth factor receptorHydrogen bondActive siteEGFR inhibitorsCetuximabStereochemistryCatalysisBiochemistryReceptorIn silicoOrganic chemistryCancerMoleculeColorectal cancerNursingGeneMedicineInternal medicineSynthesis and Biological EvaluationClick Chemistry and ApplicationsComputational Drug Discovery Methods