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Glucose-stimulated PGC-1α couples with CBP and Runx2 to mediate intervertebral disc degeneration through transactivation of ADAMTS4/5 in diet-induced obesity mice

Changchun Tseng, Yingchao Han, Zhendong Lv, Qingxin Song, Kun Wang, Hongxing Shen, Zhi Chen

2022Bone32 citationsDOI

Topics & Concepts

TransactivationRUNX2EndocrinologyTranscription factorInternal medicineBiologyMedicineGeneBiochemistrySpine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationClinical practice guidelines implementation
Glucose-stimulated PGC-1α couples with CBP and Runx2 to mediate intervertebral disc degeneration through transactivation of ADAMTS4/5 in diet-induced obesity mice | Litcius