Doxycycline-Induced Gastric Perforation
Yeahwa Hong, Christopher Staniorski, Dean Pollack, Steven S. Evans
Abstract
Esophageal and gastric mucosal injuries are well-documented adverse effects of doxycycline leading to odynophagia, chest pain, and abdominal pain. There are no clear diagnostic criteria for such adverse effects; hence, the diagnosis depends heavily on thorough history. There is a paucity of literature describing life-threatening complications from doxycycline-induced mucosal injury, such as hemorrhage and perforation. We present the first case report describing a gastric perforation from doxycycline use.
Topics & Concepts
DoxycyclineMedicineOdynophagiaPerforationAdverse effectSurgeryAbdominal painChest painGastroenterologyEsophagusInternal medicineAntibioticsMetallurgyBiologyPunchingMaterials scienceMicrobiologyPotassium and Related DisordersGastroesophageal reflux and treatmentsEsophageal and GI Pathology