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Pyoderma gangrenosum treated with secukinumab: A case report

Meghan L. McPhie, Mark G. Kirchhof

2020SAGE Open Medical Case Reports34 citationsDOIOpen Access PDF

Abstract

Pyoderma gangrenosum is a challenging disease to manage, due in part to the lack of approved treatment therapies. Recently, the emergence of biologic agents has expanded treatment options, with tumour necrosis factor alpha inhibitors being the best supported in the literature. In our report, we present a 50-year-old female with pyoderma gangrenosum who was successfully treated with the anti-interleukin-17 biologic agent, secukinumab, after failing other systemic therapies.

Topics & Concepts

SecukinumabPyoderma gangrenosumMedicineDermatologyBiologic AgentsSurgeryDiseasePathologyPsoriasisPsoriatic arthritisAutoimmune and Inflammatory DisordersOral Health Pathology and TreatmentHidradenitis Suppurativa and Treatments
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