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Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells

Kasey S. Love, Christopher P. Johnstone, Emma L. Peterman, Stephanie Gaglione, Michael E. Birnbaum, Kate E. Galloway

2025Cell Systems11 citationsDOIOpen Access PDF

Topics & Concepts

microRNATransgeneComputational biologyBiologyCell biologyGeneGenetically modified mousePrimary (astronomy)Computer scienceGeneticsAstronomyPhysicsCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryPluripotent Stem Cells Research
Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells | Litcius