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Synchronous measuring of triptolide changes in rat brain and blood and its application to a comparative pharmacokinetic study in normal and Alzheimer’s disease rats

Shuyun Zhu, Xin Wang, Zhenjia Zheng, Xian‐En Zhao, Yu Bai, Huwei Liu

2020Journal of Pharmaceutical and Biomedical Analysis68 citationsDOI

Topics & Concepts

TriptolideChemistryChromatographyDerivatizationTripterygium wilfordiiPharmacokineticsProtein precipitationReagentDetection limitTandem mass spectrometryHigh-performance liquid chromatographyMass spectrometryPharmacologyBiochemistryPathologyApoptosisMedicineAlternative medicinePhysical chemistryNatural Compounds in Disease TreatmentPharmacological Effects and Toxicity StudiesDrug Transport and Resistance Mechanisms
Synchronous measuring of triptolide changes in rat brain and blood and its application to a comparative pharmacokinetic study in normal and Alzheimer’s disease rats | Litcius