Bridging the Gap between Sequence and Structure Classifications of Proteins with AlphaFold Models
Jimin Pei, Antonina Andreeva, Sara Chuguransky, Beatriz Lázaro Pinto, Typhaine Paysan‐Lafosse, R. Dustin Schaeffer, Alex Bateman, Qian Cong, Nick V. Grishin
Topics & Concepts
Computational biologyHomology modelingStructural genomicsProtein domainSequence alignmentStructural similarityStructural motifStructural alignmentStructural Classification of Proteins databaseProtein superfamilyHomology (biology)Protein familyBiologyMultiple sequence alignmentPhylogenetic treeProtein structureUniProtGeneticsPeptide sequenceBiochemistryAmino acidGeneEnzymeProtein Structure and DynamicsRNA and protein synthesis mechanismsEnzyme Structure and Function