Swertiamarin, an active iridoid glycoside from Swertia pseudochinensis H. Hara, protects against alpha-naphthylisothiocyanate-induced cholestasis by activating the farnesoid X receptor and bile acid excretion pathway
Mengge Shi, Jie Tang, Tong Zhang, Han Han
Topics & Concepts
CholestasisUrsodeoxycholic acidIridoidBile acidPharmacologyTaurocholic acidChemistryWestern blotGlycosideBiochemistryInternal medicineBiologyEndocrinologyMedicineStereochemistryGeneDrug Transport and Resistance MechanismsPhytochemistry and Biological ActivitiesDrug-Induced Hepatotoxicity and Protection