Global trends in the increasing prevalence of the fosfomycin resistance gene in Staphylococcus aureus

Abstract

The FosB enzyme confers resistance to fosfomycin, an antibiotic used to treat various bacterial infections. In Staphylococcus aureus, the fosB gene can be either plasmidial or chromosomal, which exemplifies the adaptability and persistence of antibiotic resistance mechanisms in bacterial populations.1 The fosB gene can spread among S aureus strains and other bacteria through plasmids and confer fosfomycin resistance, which is a concern in clinical settings. The presence and distribution of antibiotic resistance genes in S aureus, such as fosB, are of paramount concern in the field of microbiology and public health.

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