Endothelial cells in pulmonary fibrosis: more than a bystander
Toyoshi Yanagihara, Christophe Guignabert, Martin Kolb
Abstract
<b>Focusing on EndMT, Wu et al. discovered that EC-like myofibroblasts are able to differentiate into myofibroblasts, resulting in a significant contribution to the pathogenesis of pulmonary fibrosis, and this process is redirected through induction of FoxA2</b> https://bit.ly/3YQvSIX
Topics & Concepts
MyofibroblastBystander effectPathogenesisPulmonary fibrosisFibrosisMedicineCancer researchPathologyImmunologyInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and TreatmentsExtracellular vesicles in disease